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Approximately 28% of the mesalamine in Asacol tablets is absorbed after oral ingestion, leaving the remainder available for topical action and excretion in the feces. This acute reaction, characterized by cramping, abdominal pain, bloody diarrhea, and occasionally by fever, headache, malaise, pruritus, rash, and conjunctivitis, has been reported after the initiation of Asacol tablets as well as other mesalamine products. 4%) of the Asacol patients discontinued Asacol therapy because of adverse events, as compared to four (4. It has been so nice to only take 2 a day as opposed to 6 of the Asacol a day and I have had more normal body functions than I have ever had. 1 times the maximum recommended human maintenance dose of Asacol of 1. Adverse events seen in clinical trials with Asacol tablets have generally been mild and reversible. 2%) of the Asacol patients discontinued Asacol therapy because of adverse events as compared to two (2. Therefore, caution should be exercised when using Asacol (or other compounds which contain or are converted to mesalamine or its metabolites) in patients with known renal dysfunction or history of renal disease. One tablet of Asacol